BDBM572741 4-(3-Pyridin-4-ylmethyl-ureido)-N-(1,2,3,4-tetrahydro-naphthalen-1-yl)-benzenesulfonamide::US11452717, Example 203

SMILES O=C(NCc1ccncc1)Nc1ccc(cc1)S(=O)(=O)NC1CCCc2ccccc12

InChI Key InChIKey=DMAFZGKDJAGFMW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 572741   

TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM572741(US11452717, Example 203 | 4-(3-Pyridin-4-ylmethyl-...)
Affinity DataEC50: <100nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
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Date in BDB:
12/4/2022
Entry Details
US Patent