BDBM573686 (S)-3- (pyrrolidin-2- ylmethyl-d2)- 1H-indol-4-ol::US11453689, Compound I-51

SMILES Oc1cccc2[nH]cc(C[C@@H]3CCCN3)c12

InChI Key InChIKey=PVFAYAZDVYXQFR-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 573686   

Target5-hydroxytryptamine receptor 2A(Human)
Mindset Pharma

US Patent
LigandPNGBDBM573686(US11453689, Compound I-51 | (S)-3- (pyrrolidin-2- ...)
Affinity DataEC50: <1.00E+3nMAssay Description:i. Prepare the assay buffer following the table below;Reagent ConcentrationTris 50 mMCaCl2  4 mMBSA 0.1% (w/v)Adjust pH to 7.4 followed by 0.2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Mindset Pharma

US Patent
LigandPNGBDBM573686(US11453689, Compound I-51 | (S)-3- (pyrrolidin-2- ...)
Affinity DataEC50: <1.00E+3nMAssay Description:Agonist activity at human 5-HT2A receptor expressed in cells assessed as increase in calcium mobilization by Calcium-6 dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed