BDBM573841 (5R,7R,8S,12aR,14R,15R,15aS,16R)-7-(2- amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-14-(6- amino-9H-purin-9-yl)-16-fluoro-15- hydroxyoctahydro-12H-5,8-methanofuro[3,2-l] [1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecine- 2,10-diolate 2,10-dioxide::US11453697, Example 5

SMILES Nc1nc2c(ncn2[C@@H]2O[C@@H]3COP(=O)(O)OC4[C@@H](COP(=O)(O)O[C@H]2C3F)O[C@@H](n2cnc3c(N)ncnc32)[C@H]4O)c(=O)[nH]1

InChI Key InChIKey=VBLXAMKAPFQPLZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 573841   

LigandChemical structure of BindingDB Monomer ID 573841BDBM573841(US11453697, Example 5 | (5R,7R,8S,12aR,14R,15R,15a...)
Affinity DataEC50:  1.10nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 573841BDBM573841(US11453697, Example 5 | (5R,7R,8S,12aR,14R,15R,15a...)
Affinity DataEC50:  1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent