BDBM573857 2-amino-9-[(5S,7R,8R,12aR,14R,15R,15aR)-14- (6-amino-9H-purin-9-yl)-15-fluoro-2,10- dihydroxy-2,10-dioxidooctahydro-12H-5,8- methanofuro[3,2-l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]-1,9- dihydro-6H-purin-6-one::US11453697, Example 21
SMILES NC1NC(N)=Nc2c1ncn2[C@@H]1O[C@H]2C[C@@H]1OP(O)(=O)OC[C@H]1O[C@H]([C@@H](F)C1OP(O)(=O)OC2)n1cnc2c(N)ncnc12
InChI Key InChIKey=NMFBAATXPJARJT-WUFZOPORSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 573857
TargetStimulator of interferon genes protein [1-379,R71H,G230A,H232R,R293Q](Human)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataEC50: 1.30nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair