BDBM573919 2-amino-9-[(2R,5R,7R,8R,10,R, 12aR,14R,15S,15aR,16R)-14-(6-amino-9H- purin-9-yl)-15-fluoro-2,10,16-trihydroxy-2,10- disulfidooctahydro-12H-5,8- methanofuro[3,2-l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]-1,9- dihydro-6H-purin-6-one (Diastereomer 1)::US11453697, Example 89

SMILES Nc1nc2c(ncn2[C@@H]2O[C@@H]3CO[P@@](=O)(S)OC4[C@@H](CO[P@@](=O)(S)O[C@H]2C3O)O[C@@H](n2cnc3c(N)ncnc32)[C@H]4F)c(=O)[nH]1

InChI Key InChIKey=WXDFCKYYDRMTTP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 573919   

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 573919BDBM573919(US11453697, Example 89 | 2-amino-9-[(2R,5R,7R,8R,1...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 573919BDBM573919(US11453697, Example 89 | 2-amino-9-[(2R,5R,7R,8R,1...)
Affinity DataEC50:  8.27E+3nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent