BDBM573960 2-amino-9- [(5R,7R,8S,12aR,14R,15S,15aR,16S)-14-(6- amino-9H-purin-9-yl)-15,16-difluoro-2,10- dioxido-2,10-disulfanyloctahydro-12H-5,8- methanofuro[3,2-l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]-1,9- dihydro-6H-purin-6-one (Diastereomer 2)::US11453697, Example 145::US11453697, Example 146

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(S)(=O)O[C@@H]3[C@@H](COP(S)(=O)O[C@@H]1[C@H]2F)O[C@H]([C@H]3F)n1cnc2c(N)ncnc12

InChI Key InChIKey=YSUIQYOGTINQIN-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 573960   

LigandPNGBDBM573960(US11453697, Example 145 | 2-amino-9- [(5R,7R,8S,12...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

LigandPNGBDBM573960(US11453697, Example 145 | 2-amino-9- [(5R,7R,8S,12...)
Affinity DataEC50:  5.60nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573960(US11453697, Example 145 | 2-amino-9- [(5R,7R,8S,12...)
Affinity DataEC50:  14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent