BDBM573990 2-amino-9-[(2R,5R,7R,8S,10R, 12aR,14R,15S,15aR,16R)-15,16-difluoro- 2,10-dihydroxy-14-(6-oxo-1,6-dihydro- 9H-purin-9-yl)-2,10-disulfidooctahydro- 12H-5,8-methanofuro[3,2- l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]- 1,9-dihydro-6H-purin-6-one (Diastereomer 1)::US11453697, Example 308

SMILES Nc1nc2c(ncn2[C@@H]2O[C@@H]3CO[P@@](=O)(S)O[C@H]4[C@H](F)[C@H](n5cnc6c(=O)[nH]cnc65)O[C@@H]4CO[P@@](=O)(S)O[C@@H]2[C@@H]3F)c(=O)[nH]1

InChI Key InChIKey=FWVIDSMWSFHGGV-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 573990   

LigandChemical structure of BindingDB Monomer ID 573990BDBM573990(US11453697, Example 308 | 2-amino-9-[(2R,5R,7R,8S,...)
Affinity DataEC50:  1.60nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 573990BDBM573990(US11453697, Example 308 | 2-amino-9-[(2R,5R,7R,8S,...)
Affinity DataEC50:  3.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent