BDBM574032 2-amino-9-[(5R,7R,8S,12aR,14R,15R,15aS)-14- (6-amino-9H-purin-9-yl)-18,18-difluoro-2,10- dihydroxy-2,10-disulfidohexahydro-14H-15,12a- (epoxymethano)-5,8-methanofuro[3,2- l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetra- decin-7(12H)-yl]-1,9-dihydro-6H-purin-6-one (Diastereomer 1)::US11453697, Example 157::US11453697, Example 159::US11453697, Example 160

SMILES Nc1nc2c(ncn2[C@@H]2O[C@@H]3COP(O)(=S)O[C@H]4[C@H]5OCC4(COP(O)(=S)O[C@@H]2C3(F)F)O[C@H]5n2cnc3c(N)ncnc32)c(=O)[nH]1

InChI Key InChIKey=FAPHJTDZMJNZHV-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 574032   

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574032BDBM574032(US11453697, Example 157 | 2-amino-9-[(5R,7R,8S,12a...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574032BDBM574032(US11453697, Example 157 | 2-amino-9-[(5R,7R,8S,12a...)
Affinity DataEC50:  7.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574032BDBM574032(US11453697, Example 157 | 2-amino-9-[(5R,7R,8S,12a...)
Affinity DataEC50:  10.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent