BDBM574069 5-amino-3- [(5R,7R,8S,12aR,14R,15S,15aR,16R)-14-(6- amino-9H-purin-9-yl)-15,16-difluoro-2,10- dihydroxy-2,10-disulfidooctahydro-12H-5,8- methanofuro[3,2- l][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetra- decin-7-yl]-3,6-dihydro-7H-[1,2,3]triazolo[4,5- d]pyrimidin-7-one (Diastereomer 1)::US11453697, Example 197::US11453697, Example 198::US11453697, Example 199

SMILES Nc1nc2c(nnn2[C@@H]2O[C@@H]3COP(O)(=S)O[C@H]4[C@H](F)[C@H](n5cnc6c(N)ncnc65)O[C@@H]4COP(O)(=S)O[C@@H]2[C@@H]3F)c(=O)[nH]1

InChI Key InChIKey=LWLRPALZYJPXGM-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 574069   

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574069BDBM574069(US11453697, Example 197 | 5-amino-3- [(5R,7R,8S,12...)
Affinity DataEC50:  1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574069BDBM574069(US11453697, Example 197 | 5-amino-3- [(5R,7R,8S,12...)
Affinity DataEC50:  19.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574069BDBM574069(US11453697, Example 197 | 5-amino-3- [(5R,7R,8S,12...)
Affinity DataEC50:  72nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent