BDBM574093 5-amino-3- [(5R,7R,8R,12aR,14R,15S,15aR,16S)-14-(6- amino-9H-purin-9-yl)-15,16-difluoro-2,10- dihydroxy-2,10-disulfidooctahydro-12H-5,8- methanofuro[3,2- l][1,3,9,11,6,2,10]tetraoxathiadiphosphacyclotetra- decin-7-yl]-3,6-dihydro-7H41,2,3]triazolo[4,5- d]pyrimidin-7-one (Diastereomer 1)::US11453697, Example 221::US11453697, Example 222::US11453697, Example 223

SMILES Nc1nc2n(nnc2c(=O)[nH]1)[C@@H]1S[C@@H]2COP(O)(=S)O[C@@H]3[C@@H](COP(O)(=S)O[C@@H]1[C@@H]2F)O[C@H]([C@H]3F)n1cnc2c(N)ncnc12

InChI Key InChIKey=DOZGTVJUJZRXSA-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 574093   

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574093(US11453697, Example 221 | 5-amino-3- [(5R,7R,8R,12...)
Affinity DataEC50: <1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574093(US11453697, Example 221 | 5-amino-3- [(5R,7R,8R,12...)
Affinity DataEC50:  60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM574093(US11453697, Example 221 | 5-amino-3- [(5R,7R,8R,12...)
Affinity DataEC50:  302nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent