BDBM574108 2-amino-9-[(5R,7R,8R,12aR,14R,15aR,16R)-14- (7-amino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3- yl)-15,15,16-trifluoro-2,10-dioxido-2,10- disulfanyloctahydro-12H-5,8-methanofuro[3,2- l][1,3,9,11,6,2,10]tetraoxathiadiphosphacyclotetra- decin-7-yl]-1,9-dihydro-6H-purin-6-one (Diastereomer 1)::US11453697, Example 236::US11453697, Example 237::US11453697, Example 238::US11453697, Example 239

SMILES Nc1nc2c(ncn2[C@@H]2S[C@@H]3COP(=O)(S)O[C@@H]4[C@@H](COP(=O)(S)O[C@@H]2[C@H]3F)O[C@@H](n2nnc3c(N)ncnc32)C4(F)F)c(=O)[nH]1

InChI Key InChIKey=DMQJHEHHWMWGBH-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 574108   

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574108BDBM574108(US11453697, Example 236 | US11453697, Example 239 ...)
Affinity DataEC50:  3.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574108BDBM574108(US11453697, Example 236 | US11453697, Example 239 ...)
Affinity DataEC50:  66.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574108BDBM574108(US11453697, Example 236 | US11453697, Example 239 ...)
Affinity DataEC50:  307nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574108BDBM574108(US11453697, Example 236 | US11453697, Example 239 ...)
Affinity DataEC50:  6.96E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent