BDBM574112 2-amino-9- [(5R,7R,8R,12aR,14R,15R,15aS,18R)-14-(6- amino-9H-purin-9-yl)-18-fluoro-2,10-dioxido- 2,10-disulfanylhexahydro-14H-15,12a- (epoxymethano)-5,8-methanofuro[3,2- l][1,3,9,11,6,2,10]tetraoxathiadiphosphacyclotetra- decin-7(12H)-yl]-1,9-dihydro-6H-purin-6-one (Diastereomer 1)::US11453697, Example 240::US11453697, Example 241::US11453697, Example 242

SMILES Nc1nc2c(ncn2[C@@H]2S[C@@H]3COP(=O)(S)O[C@H]4[C@H]5OCC4(COP(=O)(S)O[C@@H]2[C@H]3F)O[C@H]5n2cnc3c(N)ncnc32)c(=O)[nH]1

InChI Key InChIKey=GDZGPZQNJBCWOZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 574112   

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574112BDBM574112(US11453697, Example 240 | US11453697, Example 242 ...)
Affinity DataEC50:  1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574112BDBM574112(US11453697, Example 240 | US11453697, Example 242 ...)
Affinity DataEC50:  73.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574112BDBM574112(US11453697, Example 240 | US11453697, Example 242 ...)
Affinity DataEC50:  472nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent