BDBM574125 2-amino-9-[(5R,7R,8S,12aR,14R,15aS,16R)-14- (4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)-16- fluoro-2,10-dihydroxy-2,10-disulfidooctahydro- 12H-5,8-methanofuro[3,2- 1][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetra- decin-7-yl]-1,9-dihydro-6H-purin-6-one (Diastereomer 1)::US11453697, Example 257::US11453697, Example 258::US11453697, Example 259

SMILES Nc1nc2c(ncn2[C@@H]2O[C@@H]3COP(=O)(S)O[C@H]4C[C@H](c5cnn6c(N)ncnc56)O[C@@H]4COP(=O)(S)O[C@@H]2[C@@H]3F)c(=O)[nH]1

InChI Key InChIKey=FSVVMOVPOJHXOI-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 574125   

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574125BDBM574125(US11453697, Example 257 | US11453697, Example 259 ...)
Affinity DataEC50:  1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574125BDBM574125(US11453697, Example 257 | US11453697, Example 259 ...)
Affinity DataEC50:  5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 574125BDBM574125(US11453697, Example 257 | US11453697, Example 259 ...)
Affinity DataEC50:  136nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
US Patent