BDBM574314 US11458138, Example 143

SMILES CC1(Nc2nc(-c3ccc4[nH]ncc4c3)nc3cnccc23)CC1

InChI Key InChIKey=JVKXGULJDKFZRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574314   

TargetSerine/threonine-protein kinase LATS1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 574314BDBM574314(US11458138, Example 143)
Affinity DataIC50: 7nMAssay Description:The LATS1 biochemical HTRF assay was performed using the HTRF KinEASE-STK S1 kit (CisBio, catalogue number 62ST1PEC) according to manufacturer's ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent