BDBM574357 US11458138, Example 186

SMILES Cn1nccc1-c1nc(NC2(C)CCC2)c2ccncc2n1

InChI Key InChIKey=ZFZNIZVNKXAOHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 574357   

TargetSerine/threonine-protein kinase LATS1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 574357BDBM574357(US11458138, Example 186)
Affinity DataIC50: 9nMAssay Description:The LATS1 biochemical HTRF assay was performed using the HTRF KinEASE-STK S1 kit (CisBio, catalogue number 62ST1PEC) according to manufacturer's ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent

TargetSerine/threonine-protein kinase LATS2(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 574357BDBM574357(US11458138, Example 186)
Affinity DataIC50: 50nMAssay Description:Human LATS2 kinase domain protein was purchased from Carnabio (catalogue number 01-124), which harbors the catalytic domain of amino acids 553-1088, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent