BDBM575486 N,N'-2,2'-dimethyl[1,1'-biphenyl]-3,3'-diyl)bis (4-methoxy-5-((((R)-5-oxotetrahydrofuran-3-yl) amino)methyl)picolinamide)::US11459339, Example 74

SMILES COc1cc(ncc1CN[C@H]1COC(=O)C1)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(OC)c(CN[C@H]3COC(=O)C3)cn2)c1C

InChI Key InChIKey=DUOQPIFNZSCYCD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575486   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575486(US11459339, Example 74 | N,N'-2,2'-dimethyl[1,1'-b...)
Affinity DataIC50: 0.140nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2022
Entry Details
US Patent