BDBM575493 N,N'-(2,2'-dimethyl-[1,1'- biphenyl]-3,3'-diyl)bis(5-(((2- methoxyethyl)amino)methyl)- 4-methylpicolinamide)::US11459339, Example 7

SMILES COCCNCc1cnc(cc1C)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(C)c(CNCCOC)cn2)c1C

InChI Key InChIKey=IRKOSFQUMNLLHE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575493   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575493(US11459339, Example 7 | N,N'-(2,2'-dimethyl-[1,1'-...)
Affinity DataIC50: 0.0960nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent