BDBM575498 N,N'-(2,2'-dimethyl-[1,1'-biphenyl]-3,3'-diyl)bis(4- methoxy-5-(((2-(methylsulfonyl)ethyl)amino) methyl)picolinamide)::US11459339, Example 80

SMILES COc1cc(ncc1CNCCS(C)(=O)=O)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(OC)c(CNCCS(C)(=O)=O)cn2)c1C

InChI Key InChIKey=OAMLWVKMKTVSJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575498   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575498(US11459339, Example 80 | N,N'-(2,2'-dimethyl-[1,1'...)
Affinity DataIC50: 0.0820nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent