BDBM575499 N,N'-(2,2'-dimethyl-[1,1'- biphenyl]-3,3'-diyl)bis(5- ((((1-hydroxycyclopropyl) methyl)amino)methyl)-4- methylpicolinamide)::US11459339, Example 10

SMILES Cc1cc(ncc1CNCC1(O)CC1)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(C)c(CNCC3(O)CC3)cn2)c1C

InChI Key InChIKey=QIIIYNZZRMJGHQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575499   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575499(US11459339, Example 10 | N,N'-(2,2'-dimethyl-[1,1'...)
Affinity DataIC50: 0.280nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent