BDBM575515 N,N'-(2,2'-dimethyl-[1,1'- biphenyl]-3,3'-diyl)bis(5- ((((3S,4R)-3-hydroxytetrahydro- 2H-pyran-4-yl)amino)methyl)-4- methylpicolinamide)::US11459339, Example 18

SMILES Cc1cc(ncc1CN[C@@H]1CCOC[C@H]1O)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(C)c(CN[C@@H]3CCOC[C@H]3O)cn2)c1C

InChI Key InChIKey=HWTBRLAHJYCDRC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575515   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575515(US11459339, Example 18 | N,N'-(2,2'-dimethyl-[1,1'...)
Affinity DataIC50: 0.340nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent