BDBM575518 N,N'-(2,2'-dimethyl-[1,1'-biphenyl]- 3,3'-diyl)bis(4-methoxy-5-(((2-((1- oxidotetrahydro-1lambda6-thiophen-1- ylidene)amino)ethyl)amino)methyl) picolinamide)::US11459339, Example 90

SMILES COc1cc(ncc1CNCCN=S1(=O)CCCC1)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(OC)c(CNCCN=S3(=O)CCCC3)cn2)c1C

InChI Key InChIKey=DZXFQZWBAKMVEJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575518   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575518(US11459339, Example 90 | N,N'-(2,2'-dimethyl-[1,1'...)
Affinity DataIC50: 0.360nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2022
Entry Details
US Patent