BDBM575523 US11459339, Example 22::dimethyl 2,2'-((((((2,2'- dimethyl-[1,1'-biphenyl]-3,3'- diyl)bis(azanediyl))bis(carbonyl)) bis(4-methylpyridine-6,3- diyl))bis(methylene))bis(azanediyl)) (2S,2'S)-bis(3-hydroxypropanoate)

SMILES COC(=O)[C@H](CO)NCc1cnc(cc1C)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(C)c(CN[C@@H](CO)C(=O)OC)cn2)c1C

InChI Key InChIKey=AKZAXALSIVLMJE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575523   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575523(US11459339, Example 22 | dimethyl 2,2'-((((((2,2'-...)
Affinity DataIC50: 0.280nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent