BDBM575525 (2S,2'S)-2,2'-((((((2,2'- dimethyl-[1,1'-biphenyl]3,3'- diyl)bis(azanediyl))bis(carbonyl)) bis(4-methylpyridine-6,3-diyl)) bis(methylene))bis(azanediyl))bis (3-hydroxypropanoic acid)::US11459339, Example 23

SMILES Cc1cc(ncc1CN[C@@H](CO)C(O)=O)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(C)c(CN[C@@H](CO)C(O)=O)cn2)c1C

InChI Key InChIKey=FSHLEFXKQCSQBA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575525   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575525(US11459339, Example 23 | (2S,2'S)-2,2'-((((((2,2'-...)
Affinity DataIC50: 0.310nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent