BDBM575565 N,N'-(2,2'-dimethyl-[1,1'- biphenyl]-3,3'-diyl)bis(5- ((((S)-1- hydroxypropan-2-yl)amino) methyl)-4-methoxypicolinamide)::US11459339, Example 43

SMILES COc1cc(ncc1CN[C@@H](C)CO)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(OC)c(CN[C@@H](C)CO)cn2)c1C

InChI Key InChIKey=YAQNOVOMQGROMI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575565   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575565(US11459339, Example 43 | N,N'-(2,2'-dimethyl-[1,1'...)
Affinity DataIC50: 0.290nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent