BDBM575579 N,N'-(2,2'-dimethyl-[1,1'- biphenyl]-3,3'-diyl)bis(4- methoxy-5-(((R)-3- methoxypyrrolidin-1- yl)methyl)picolinamide)::US11459339, Example 50

SMILES CO[C@@H]1CCN(Cc2cnc(cc2OC)C(=O)Nc2cccc(c2C)-c2cccc(NC(=O)c3cc(OC)c(CN4CC[C@H](C4)OC)cn3)c2C)C1

InChI Key InChIKey=QLDNZGUSOMPIIO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575579   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575579(US11459339, Example 50 | N,N'-(2,2'-dimethyl-[1,1'...)
Affinity DataIC50: 0.330nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2022
Entry Details
US Patent