BDBM575581 N,N'-(2,2'-dimethyl-[1,1'- biphenyl]-3,3'-diyl)bis(4- methoxy-5-((3-methoxyazetidin- 1-yl)methyl)picolinamide)::US11459339, Example 51

SMILES COC1CN(Cc2cnc(cc2OC)C(=O)Nc2cccc(c2C)-c2cccc(NC(=O)c3cc(OC)c(CN4CC(C4)OC)cn3)c2C)C1

InChI Key InChIKey=OXNFKHWJINVQNF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575581   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575581(US11459339, Example 51 | N,N'-(2,2'-dimethyl-[1,1'...)
Affinity DataIC50: 0.220nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent