BDBM575585 N,N'-(2,2'-dimethyl-[1,1'- biphenyl]-3,3'-diyl)bis(5- ((((1s,3s)-3- hydroxycyclobutyl)amino) methyl)-4-methoxypicolinamide)::US11459339, Example 53

SMILES COc1cc(C(=O)Nc2cccc(-c3cccc(NC(=O)c4cc(OC)c(CN[C@H]5C[C@@H](O)C5)cn4)c3C)c2C)ncc1CN[C@H]1C[C@@H](O)C1

InChI Key InChIKey=NLDGQRRNKRLZEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575585   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575585BDBM575585(US11459339, Example 53 | N,N'-(2,2'-dimethyl-[1,1'...)
Affinity DataIC50: 0.150nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent