BDBM575597 (3S,3'S)-4,4'-((((((2,2'-dimethyl- [1,1'-biphenyl]-3,3'-diyl)bis (azanediyl))bis(carbonyl))bis(4- methoxypyridine-6,3-diyl))bis (methylene))bis(azanediyl)bis (3-hydroxybutanoic acid)::US11459339, Example 59

SMILES COc1cc(ncc1CNC[C@@H](O)CC(O)=O)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(OC)c(CNC[C@@H](O)CC(O)=O)cn2)c1C

InChI Key InChIKey=IUMBTXQIOCHRGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575597   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575597(US11459339, Example 59 | (3S,3'S)-4,4'-((((((2,2'-...)
Affinity DataIC50: 0.310nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent