BDBM575599 (1s,1's,3s,3's)-3,3'-((((((2,2'- dimethyl-[1,1'-biphenyl]-3,3'- diyl)bis(azanediyl))bis(carbonyl)) bis(4-methoxypyridine-6,3-diyl)) bis(methylene))bis(azanediyl))bis (cyclobutane-1-carboxylic acid)::US11459339, Example 60

SMILES COc1cc(C(=O)Nc2cccc(-c3cccc(NC(=O)c4cc(OC)c(CN[C@H]5C[C@@H](C(=O)O)C5)cn4)c3C)c2C)ncc1CN[C@H]1C[C@@H](C(=O)O)C1

InChI Key InChIKey=KQADNCFTJLVFME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575599   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 575599BDBM575599(US11459339, Example 60 | (1s,1's,3s,3's)-3,3'-((((...)
Affinity DataIC50: 0.0340nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent