BDBM575608 (3S,3'S)-4,4'-((((((2,2'-dimethyl-[1,1'- biphenyl]-3,3'-diyl)bis(azanediyl))bis (carbonyl))bis(4-cyclopropylpyridine- 6,3-diyl))bis(methylene))bis(azanediyl)) bis(3-hydroxybutanoic acid)::US11459339, Example 136

SMILES Cc1c(NC(=O)c2cc(C3CC3)c(CNC[C@@H](O)CC(O)=O)cn2)cccc1-c1cccc(NC(=O)c2cc(C3CC3)c(CNC[C@@H](O)CC(O)=O)cn2)c1C

InChI Key InChIKey=NOVFYQKDLYIOMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575608   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575608(US11459339, Example 136 | (3S,3'S)-4,4'-((((((2,2'...)
Affinity DataIC50: 0.320nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
US Patent