BDBM575615 N,N'-(2,2'-dimethyl-11,1'- biphenyl]-3,3'-diyl)bis(4- methoxy-5-((((S)-2- oxotetrahydrofuran-3-yl) amino)methyl)picolinamide)::US11459339, Example 68

SMILES COc1cc(ncc1CN[C@H]1CCOC1=O)C(=O)Nc1cccc(c1C)-c1cccc(NC(=O)c2cc(OC)c(CN[C@H]3CCOC3=O)cn2)c1C

InChI Key InChIKey=UTCZJWNVJBUCTM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575615   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Abbisko Therapeutics

US Patent
LigandPNGBDBM575615(US11459339, Example 68 | N,N'-(2,2'-dimethyl-11,1'...)
Affinity DataIC50: 0.310nMAssay Description:The effect of compounds and positive compounds of the examples of the present invention on the interaction between PD-1 and PD-L1 was determined by t...More data for this Ligand-Target Pair
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Date in BDB:
12/7/2022
Entry Details
US Patent