BDBM575896 US11466016, Example 24::endo-8-[7-(3,4- dichloro- 2-methyl-2H- indazol-5- yl)-5H-pyrrolo [2,3-b]pyrazin- 3-yl]-8- azabicyclo[3.2.1] octan-3-amine, methanesulfonic acid salt
SMILES Cn1nc2ccc(-c3c[nH]c4nc(cnc34)N3[C@H]4CC[C@@H]3C[C@H](N)C4)c(Cl)c2c1Cl
InChI Key
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 575896
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Otsuka Pharmaceutical
US Patent
Otsuka Pharmaceutical
US Patent
Affinity DataIC50: 4.30nMAssay Description:SHP2 activity was monitored by measuring the conversion of the surrogate substrate 6,8-difluoromethylumbelliferyl phosphate (DiFMUP) to the fluoresce...More data for this Ligand-Target Pair