BDBM576130 2-amino-9- [(5R,7R,8S,12aR,14R,15S,15aR,16R)- 15,16-difluoro-10-hydroxy-14-(6-oxo- 1,6-dihydro-9H-purin-9-yl)-2-sulfanyl- 2,10-disulfidooctahydro-12H-5,8- methanofuro[3,2-1][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7- yl]-1,9-dihydro-6H-purin-6-one::US11466047, Example 27

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(S)(=S)O[C@@H]3[C@@H](COP(O)(=S)O[C@@H]1[C@@H]2F)O[C@H]([C@H]3F)n1cnc2c1nc[nH]c2=O

InChI Key InChIKey=HMNAJGIHVNCEMM-UHFFFAOYSA-N

Data  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576130   

TargetStimulator of interferon genes protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM576130(US11466047, Example 27 | 2-amino-9- [(5R,7R,8S,12a...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
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Date in BDB:
12/11/2022
Entry Details
US Patent