BDBM577553 2-[[1 -methyl-3-[(3S,4R)-4-methyltetrahydrofuran-3- yl]oxy-1 H-pyrazol-4-yl]amino]-7-[(3R,4R)-4-methyltetrahydrofuran-3-yl]pyrrolo[2,3-d]pyrimidine-6-carbonitrile::WO2022263472, Example 3

SMILES C[C@@H]1COCC1Oc1nn(C)cc1Nc1ncc2cc(C#N)n([C@H]3COC[C@@H]3C)c2n1

InChI Key InChIKey=KZMVTCAXLIPFAD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 577553   

LigandPNGBDBM577553(WO2022263472, Example 3 | 2-[[1 -methyl-3-[(3S,4R)...)
Affinity DataIC50: 4nMAssay Description:The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
WIPO WO2022263472

LigandPNGBDBM577553(WO2022263472, Example 3 | 2-[[1 -methyl-3-[(3S,4R)...)
Affinity DataIC50: 5nMAssay Description:The measurements of the activities were made using a LRRK2-G2019S(human) Kinase activity assay as described hereunder. The potency of compounds was e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
WIPO WO2022263472