BDBM57806 1-[1-(1-benzofuran-2-yl)ethylideneamino]-3-(3-methylphenyl)thiourea::1-[1-(2-benzofuranyl)ethylideneamino]-3-(3-methylphenyl)thiourea::1-[1-(benzofuran-2-yl)ethylideneamino]-3-(m-tolyl)thiourea::MLS000391554::SMR000260589::cid_4157752

SMILES CC(=NNC(=S)Nc1cccc(C)c1)c1cc2ccccc2o1

InChI Key InChIKey=SAIXYCIKEWSEGP-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 57806   

TargetUrease [D459Y,K653P](Jack bean)
University of Karachi

LigandPNGBDBM57806(1-[1-(2-benzofuranyl)ethylideneamino]-3-(3-methylp...)
Affinity DataIC50: 283nMpH: 8.2Assay Description:The mixture of this enzyme inhibition assay was composed of 10 µL of enzyme (5 U/mL) and 10 µL of each test compound in the series (3a-3s) in 40 µL b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2015
Entry Details Article
PubMed
TargetMitochondrial import inner membrane translocase subunit TIM10(Baker's yeast)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM57806(1-[1-(2-benzofuranyl)ethylideneamino]-3-(3-methylp...)
Affinity DataIC50: 4.77E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM57806(1-[1-(2-benzofuranyl)ethylideneamino]-3-(3-methylp...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay