BDBM578776 4-{4-[hydroxy(1-methyl-1H-pyrazol-4-yl)methyl]-2-({2-[3-methyl-6-methylcarbamoyl)-1H-indol-1-yl]propanoyl}amino)phenyl}butanoic acid::US11479550, Example 18-3

SMILES CNC(=O)c1ccc2c(C)cn(C(C)C(=O)Nc3cc(Cc4cnn(CO)c4)ccc3CCCC(O)=O)c2c1

InChI Key InChIKey=TYTIYYNMSTZKGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 578776   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM578776(US11479550, Example 18-3 | 4-{4-[hydroxy(1-methyl-...)
Affinity DataIC50: 6.20nMAssay Description:CHO cells expressing human EP4 receptor subtypes were prepared according to the methods of Nishigaki et al. (Non-Patent Literature 4), and used for e...More data for this Ligand-Target Pair
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Date in BDB:
12/30/2022
Entry Details
US Patent