BDBM579074 4-(aminomethyl)-6-(5-(2,4- dimethoxyphenoxy)pyridin-3-yl)phthalazin- 1(2H)-one::US11479551, Example 4-162::US11492351, Example 4-162

SMILES COc1ccc(Oc2cncc(-c3ccc4c(=O)[nH]nc(CN)c4c3)c2)c(OC)c1

InChI Key InChIKey=OGBXRGPNYVWSQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 579074   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 579074BDBM579074(US11492351, Example 4-162 | 4-(aminomethyl)-6-(5-(...)
Affinity DataIC50: 842nMAssay Description:The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/20/2023
Entry Details
US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 579074BDBM579074(US11492351, Example 4-162 | 4-(aminomethyl)-6-(5-(...)
Affinity DataIC50: 842nMAssay Description:The assay uses purified human, PRMT5 enzyme to convert S-adenosyl-L-[methyl-3H]methionine plus histone H4 L-arginine to S-adenosyl-L-homocysteine plu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent