BDBM579108 3-methoxyisonicotinonitrile::US11479552, Example 2

SMILES CO[C@@H]1CN(CC[C@@H]1[C@H]1C[C@@H]2CC[C@H](C1)N2[C@H](C(C)C)C(N)=O)c1ncc(F)cn1

InChI Key InChIKey=JSWRKGMZUZOKEL-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 579108   

TargetOrexin receptor type 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579108(3-methoxyisonicotinonitrile | US11479552, Example ...)
Affinity DataEC50:  3.08nMAssay Description:HEK293 (human embryonic kidney 293) cells with forced expression of human OX1R (hOX1R) or human OX2R (hOX2R) were seeded in a 384-well microplate (Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579108(3-methoxyisonicotinonitrile | US11479552, Example ...)
Affinity DataEC50: >100nMAssay Description:HEK293 (human embryonic kidney 293) cells with forced expression of human OX1R (hOX1R) or human OX2R (hOX2R) were seeded in a 384-well microplate (Gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent