BDBM579110 (R)-2-cyclopropyl-2-((1R,3S,5S)-3-((2S, 4S)-1-(5-fluoropyrimidin-2-yl)-2-methylpiperidin-4-yl)-8-azabicyclo[3.2.1]octan-8-yl)acetamide::US11479552, Example 4

SMILES C[C@H]1C[C@H](CCN1c1ncc(F)cn1)[C@H]1C[C@@H]2CC[C@H](C1)N2[C@H](C1CC1)C(N)=O

InChI Key InChIKey=OLGODMIRYXFSBW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 579110   

TargetOrexin receptor type 2(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579110((R)-2-cyclopropyl-2-((1R,3S,5S)-3-((2S, 4S)-1-(5-f...)
Affinity DataEC50:  4.40nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM579110((R)-2-cyclopropyl-2-((1R,3S,5S)-3-((2S, 4S)-1-(5-f...)
Affinity DataEC50:  3.90E+3nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
US Patent