BDBM579546 US11484525, Compound DD-159

SMILES CN(C)[C@H](CNC(=O)NCCc1cn(CCSSCCN=[N+]=[N-])nn1)Cc1ccc(O)cc1

InChI Key InChIKey=RBURBNOCQBNJEY-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 579546   

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM579546(US11484525, Compound DD-159)
Affinity DataKi:  34nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

TargetMu-type opioid receptor [N127C](Human)
University of California

US Patent
LigandPNGBDBM579546(US11484525, Compound DD-159)
Affinity DataKi:  420nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM579546(US11484525, Compound DD-159)
Affinity DataKi:  1.50E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
University of California

US Patent
LigandPNGBDBM579546(US11484525, Compound DD-159)
Affinity DataKi:  3.90E+3nMAssay Description:Each compound was initially tested at 20 μM and was incubated with 3H-DPN at a concentration equal to the Kd (0.4 nM) of the radioligand in _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent