BDBM579878 N-(3-(4,7- dihydro- thieno [2,3-c] pyridin- 6(5H)- yl)-2- hydroxy-::US11485731, Example 1AD

SMILES OC(CNC(=O)N1CCCC(C1)c1ccccc1)CN1CCc2ccsc2C1

InChI Key InChIKey=HITBJVCMKIWVNO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579878   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Argonaut Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 579878BDBM579878(US11485731, Example 1AD | N-(3-(4,7- dihydro- thie...)
Affinity DataIC50: 652nMAssay Description:A PRMT5 chemiluminescent assay was used to measure the IC50 activity of PRMT5 of the compounds of Examples 1A to 7 above. Biotinylated histone peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent