BDBM579945 2-hydroxy-3-(1,2,3,4- tetrahydro- isoquinolin-2- yl)propyl pyrrolidine-1- carboxylate::US11485731, Example 3C

SMILES OC(COC(=O)N1CCCC1)CN1CCc2ccccc2C1

InChI Key InChIKey=RLVRVWXCOBSNSE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579945   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Argonaut Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 579945BDBM579945(US11485731, Example 3C | 2-hydroxy-3-(1,2,3,4- tet...)
Affinity DataIC50: 9.56E+3nMAssay Description:A PRMT5 chemiluminescent assay was used to measure the IC50 activity of PRMT5 of the compounds of Examples 1A to 7 above. Biotinylated histone peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent