BDBM579975 3-(6,7- dihydro- thieno[3,2- c]pyridin- 5(4H)-yl)- 2-hydroxy- propyl 3- phenyl-::US11485731, Example 4AC

SMILES OC(COC(=O)N1CCCC(C1)c1ccccc1)CN1CCc2sccc2C1

InChI Key InChIKey=JMIQDMQDHKQERU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579975   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Argonaut Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 579975BDBM579975(US11485731, Example 4AC | 3-(6,7- dihydro- thieno[...)
Affinity DataIC50: 374nMAssay Description:A PRMT5 chemiluminescent assay was used to measure the IC50 activity of PRMT5 of the compounds of Examples 1A to 7 above. Biotinylated histone peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent