BDBM579989 N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)propyl)-3-phenyl pyrrolidine-1-carboxamide (prepared according to Scheme 6)::US11485731, Example 6A

SMILES O=C(NCCCN1CCc2ccccc2C1)N1CCC(C1)c1ccccc1

InChI Key InChIKey=LKQDIWQNXVMDDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 579989   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Argonaut Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 579989BDBM579989(US11485731, Example 6A | N-(3-(3,4-dihydroisoquino...)
Affinity DataIC50: 939nMAssay Description:A PRMT5 chemiluminescent assay was used to measure the IC50 activity of PRMT5 of the compounds of Examples 1A to 7 above. Biotinylated histone peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2023
Entry Details
US Patent