BDBM5805 6-(3,4-dichlorophenyl)-5-(4-methoxyphenyl)furo[2,3-d]pyrimidin-4-amine::furo[2,3-d]pyrimidine deriv. 7a

SMILES COc1ccc(cc1)-c1c(oc2ncnc(N)c12)-c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=WATYTGMUDRNMSO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5805   

TargetAngiopoietin-1 receptor(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM5805(6-(3,4-dichlorophenyl)-5-(4-methoxyphenyl)furo[2,3...)
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM5805(6-(3,4-dichlorophenyl)-5-(4-methoxyphenyl)furo[2,3...)
Affinity DataIC50: 1.78E+3nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2005
Entry Details Article
PubMed
LigandPNGBDBM5805(6-(3,4-dichlorophenyl)-5-(4-methoxyphenyl)furo[2,3...)
Affinity DataIC50: 2.00E+4nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2005
Entry Details Article
PubMed