BDBM5813 N-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimidin-5-yl]phenyl}-3-chlorobenzene-1-sulfonamide::furo[2,3-d]pyrimidine deriv. 7i

SMILES COc1ccc(cc1)-c1oc2ncnc(N)c2c1-c1ccc(NS(=O)(=O)c2cccc(Cl)c2)cc1

InChI Key InChIKey=JFCWIJFRSKCJGB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5813   

TargetAngiopoietin-1 receptor(Human)
Glaxosmithkline

LigandPNGBDBM5813(N-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...)
Affinity DataIC50: 851nMpH: 7.5 T: 2°CAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/7/2005
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Glaxosmithkline

LigandPNGBDBM5813(N-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...)
Affinity DataIC50: 851nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed