BDBM581319 US11504381, Compound 2::US11548866, Compound 2

SMILES CC(=O)Nc1cc(cnc1N1CCN(CC(O)=O)CC1c1ccc(Cl)cc1)C(F)(F)F

InChI Key InChIKey=KLWLMSCLTIAYHT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581319   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Ligature Therapeutics

US Patent
LigandPNGBDBM581319(US11504381, Compound 2 | US11548866, Compound 2)
Affinity DataKi:  1.18E+5nMAssay Description:The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Ligature Therapeutics

US Patent
LigandPNGBDBM581319(US11504381, Compound 2 | US11548866, Compound 2)
Affinity DataKi:  1.18E+5nMAssay Description:The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent