BDBM581321 US11504381, Compound 4::US11548866, Compound 4

SMILES Cc1cc(Cl)ccc1C1CN(CCN1c1ncc(Cl)cc1N)C(=O)CC(O)=O

InChI Key InChIKey=SDWKLBLPXMYQRW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581321   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Ligature Therapeutics

US Patent
LigandPNGBDBM581321(US11504381, Compound 4 | US11548866, Compound 4)
Affinity DataKi:  1.07E+5nMAssay Description:The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Ligature Therapeutics

US Patent
LigandPNGBDBM581321(US11504381, Compound 4 | US11548866, Compound 4)
Affinity DataKi:  1.07E+5nMAssay Description:The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent