BDBM581329 US11504381, Compound 12::US11548866, Compound 12

SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)C1CNCCN1

InChI Key InChIKey=SZLHHILGNRJTSA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581329   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Ligature Therapeutics

US Patent
LigandPNGBDBM581329(US11504381, Compound 12 | US11548866, Compound 12)
Affinity DataKi: >2.50E+5nMAssay Description:The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Ligature Therapeutics

US Patent
LigandPNGBDBM581329(US11504381, Compound 12 | US11548866, Compound 12)
Affinity DataKi: >2.50E+5nMAssay Description:The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent