BDBM581347 US11504381, Compound 30::US11548866, Compound 30

SMILES CC(C)(C)C[C@H]1CN(C[C@H](N1c1ncc(Cl)cc1N)c1ccc(Cl)cc1)C(=O)CC(O)=O

InChI Key InChIKey=DHNNFPMNWVKVKV-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 581347   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Ligature Therapeutics

US Patent
LigandPNGBDBM581347(US11504381, Compound 30 | US11548866, Compound 30)
Affinity DataKi:  800nMAssay Description:The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Ligature Therapeutics

US Patent
LigandPNGBDBM581347(US11504381, Compound 30 | US11548866, Compound 30)
Affinity DataKi:  800nMAssay Description:The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2023
Entry Details
US Patent